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Analyzing downstream targets of Beauveria bassiana gelsolin duing conidal development

ABSTRACT: Comparative proteomics, between the wild type and delta BbGel1 strains grown on the surface of culture media, is performed to explore the downstream targets of Beauveria bassiana gelsolin during conidiation .

INSTRUMENT(S): LTQ Orbitrap

ORGANISM(S): Beauveria Bassiana (strain Arsef 2860) (white Muscardine Disease Fungus) (tritirachium Shiotae)

TISSUE(S): Cell Culture

SUBMITTER: Sheng-hua Ying

LAB HEAD: Sheng-hua Ying

PROVIDER: PXD003618 | Pride | 2016-09-26

REPOSITORIES: Pride

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The cellular proteome is affected by a gelsolin (BbGEL1) during morphological transitions in aerobic surface versus liquid growth in the entomopathogenic fungus Beauveria bassiana.

He Pu-Hong PH Dong Wei-Xia WX Chu Xin-Ling XL Feng Ming-Guang MG Ying Sheng-Hua SH

Environmental microbiology 20160913 11

The gelsolin superfamily includes seven protein members: gelsolin, villin, adseverin, CapG, advillin, supervillin and flightless I. The gelsolin proteins are actin-binding proteins that contain three or six gelsolin-like domains, and they play important roles in remodelling actin dynamics and cellular processes in eukaryotes. The entomopathogenic fungus Beauveria bassiana expresses a unique CapG protein (BbGEL1) that contains three gelsolin-like domains. BbGEL1p is associated with actin during m ...[more]

PMID: 27554994

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