Aortic Aneurysm iTRAQ HiRIEF proteomics

ABSTRACT: Conducted proteomics on samples from patients with aortic aneurysm and from non-dilated controls. Furthermore, we investigated both patients with bicuspid aortic valves (BAV) and also the more normal tricuspid aortic valves (TAV). The aim was to elucidate the molecular mechanisms behind the higher propensity of BAV patients to develop aorta dilation and consequent aortic aneurysm.

INSTRUMENT(S):

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Aorta, Aortic Endothelial Cell

DISEASE(S): Aortic Aneurysm

SUBMITTER: Rui Branca  

LAB HEAD: Janne Lehtiö

PROVIDER: PXD003702 | Pride | 2016-12-23

REPOSITORIES: Pride