Proteomics

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Comparative proteomic analysis of Toxoplama gondii PRU oocyst during sporulation


ABSTRACT: The comparative proteomics research of Toxoplasma gondii oocyst during sporulation

INSTRUMENT(S): Q Exactive

ORGANISM(S): Toxoplasma Gondii Type Iii

TISSUE(S): Oocyte

DISEASE(S): Wounds And Injuries

SUBMITTER: chunxue zhou  

LAB HEAD: Xingquan zhu

PROVIDER: PXD003765 | Pride | 2016-07-21

REPOSITORIES: Pride

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Publications

Global iTRAQ-based proteomic profiling of Toxoplasma gondii oocysts during sporulation.

Zhou Chun-Xue CX   Zhu Xing-Quan XQ   Elsheikha Hany M HM   He Shuai S   Li Qian Q   Zhou Dong-Hui DH   Suo Xun X  

Journal of proteomics 20160712


<h4>Unlabelled</h4>Toxoplasma gondii is a medically and economically important protozoan parasite. However, the molecular mechanisms of its sporulation remain largely unknown. Here, we applied iTRAQ coupled with 2D LC-MS/MS proteomic analysis to investigate the proteomic expression profile of T. gondii oocysts during sporulation. Of the 2095 non-redundant proteins identified, 587 were identified as differentially expressed proteins (DEPs). Based on Gene Ontology enrichment and KEGG pathway analy  ...[more]

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