Studying the core circuitry of pluripotency by selective isolation of chromatin-associated proteins

ABSTRACT: Here we have developed a method to identify chromatin-bound partners of a protein of interest by selective isolation of chromatin-associated proteins (SICAP) followed by mass spectrometry. We applied SICAP to identify chromatin-binding proteins associated to Oct4, Sox2 and Nanog in mouse embryonic stem (ES) cells.

INSTRUMENT(S):

ORGANISM(S): Mus Musculus (mouse)

TISSUE(S): Embryonic Stem Cell

SUBMITTER: Mahmoud Reza Rafiee  

LAB HEAD: Prof. Dr. Jeroen Krijgsveld

PROVIDER: PXD003798 | Pride | 2016-12-19

REPOSITORIES: Pride