Ontology highlight
ABSTRACT:
INSTRUMENT(S): LTQ Orbitap Discovery
ORGANISM(S): Leishmania Donovani
TISSUE(S): Tissue Not Applicable To Dataset
DISEASE(S): Visceral Leishmaniasis
SUBMITTER: Shalini Singh
LAB HEAD: Professsor Vikash Kumar Dubey
PROVIDER: PXD003815 | Pride | 2016-04-21
REPOSITORIES: Pride
Singh Shalini S Dubey Vikash Kumar VK
PloS one 20160428 4
We have earlier reported antileishmanial activity of hypericin by spermidine starvation. In the current report, we have used label free proteome quantitation approach to identify differentially modulated proteins after hypericin treatment. A total of 141 proteins were found to be differentially regulated with ANOVA P value less than 0.05 in hypericin treated Leishmania promastigotes. Differentially modulated proteins have been broadly classified under nine major categories. Increase in ribosomal ...[more]