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Protein profiling of Chlamydia trachomatis growth forms

ABSTRACT: By comprehensive quantitative proteome analysis we characterize the three growth forms elementary body (EB), reticulate body (RB) and aberrant reticulate body (ARB) of Chlamydia trachomatis genital strain D/UW-3/CX

INSTRUMENT(S): LTQ Orbitrap XL

ORGANISM(S): Chlamydia Trachomatis (strain D/uw-3/cx)

DISEASE(S): Bacterial Infectious Disease

SUBMITTER: Ole Østergaard

LAB HEAD: Ole Østergaard

PROVIDER: PXD003883 | Pride | 2017-01-04

REPOSITORIES: Pride

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Quantitative Protein Profiling of Chlamydia trachomatis Growth Forms Reveals Defense Strategies Against Tryptophan Starvation.

Østergaard Ole O Follmann Frank F Olsen Anja W AW Heegaard Niels H NH Andersen Peter P Rosenkrands Ida I

Molecular & cellular proteomics : MCP 20161026 12

Chlamydia trachomatis is one of the most common sexually transmitted bacterial pathogens in humans. The infection is often asymptomatic and can lead to chronic manifestations. The infectious elementary body and the replicating reticulate body are the two growth forms in the normal developmental cycle. Under the influence of interferon-γ, the normal cycle is disrupted because of tryptophan degradation, leading to a third persistent form, the aberrant reticulate body.For the genital strain C. trac ...[more]

PMID: 27784728

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