Proteomics profiling of early retina degeneration of RCS rats
Ontology highlight
ABSTRACT:
INSTRUMENT(S): LTQ Orbitrap Velos
ORGANISM(S): Rattus Norvegicus (rat)
TISSUE(S): Retina
DISEASE(S): Retinitis Pigmentosa
SUBMITTER: 
Martin Ju
LAB HEAD: ZhengQin Yin
PROVIDER: PXD004094 | Pride | 2017-07-24
REPOSITORIES: Pride
Publications
Proteomic profiling of early degenerative retina of RCS rats.
Zhu Zhi-Hong ZH Fu Yan Y Weng Chuan-Huang CH Zhao Cong-Jian CJ Yin Zheng-Qin ZQ
International journal of ophthalmology 20170618 6
<h4>Aim</h4>To identify the underlying cellular and molecular changes in retinitis pigmentosa (RP).<h4>Methods</h4>Label-free quantification-based proteomics analysis, with its advantages of being more economic and consisting of simpler procedures, has been used with increasing frequency in modern biological research. Dystrophic RCS rats, the first laboratory animal model for the study of RP, possess a similar pathological course as human beings with the diseases. Thus, we employed a comparative ...[more]
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