Proteomics

Dataset Information

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Quantitative proteomic analysis of the hemolymph from Bithynia siamensis goniomphalos infected with Opisthorchis viverrini


ABSTRACT: We have performed a quantitative proteomic analysis of the hemocytes and plasma proteins from O. viverrini-infected Bithynia siamensis goniomphalos snails using SWATH-MS. The dataset contains validation SWATH-MS data and Skyline results plus the sample-specific libraries.

INSTRUMENT(S):

ORGANISM(S): Bithynia Siamensis Goniomphalos

TISSUE(S): Hemolymph

SUBMITTER: Javier Sotillo  

LAB HEAD: Alex Loukas

PROVIDER: PXD004121 | Pride | 2016-10-17

REPOSITORIES: Pride

Dataset's files

Source:
Action DRS
Bythinia_database_DECOY.fasta Fasta
Hemocyte_0h_Rep1.comet.pep.xml Pepxml
Hemocyte_0h_Rep1.tandem.pep.xml Pepxml
Hemocyte_0h_Rep1.wiff Wiff
Hemocyte_0h_Rep1.wiff.scan Wiff
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Publications

Differential Protein Expression in the Hemolymph of Bithynia siamensis goniomphalos Infected with Opisthorchis viverrini.

Suwannatrai Kulwadee K   Suwannatrai Apiporn A   Tabsripair Pairat P   Welbat Jariya Umka JU   Tangkawattana Sirikachorn S   Cantacessi Cinzia C   Mulvenna Jason J   Tesana Smarn S   Loukas Alex A   Sotillo Javier J  

PLoS neglected tropical diseases 20161128 11


Bithynia siamensis goniomphalos is a freshwater snail that serves as the first intermediate host of the human liver fluke Opisthorchis viverrini. This parasite is a major public health problem in different countries throughout the Greater Mekong sub-region (Thailand, southern Vietnam, Lao PDR and Cambodia). Chronic O. viverrini infection also results in a gradual increase of fibrotic tissues in the biliary tract that are associated with hepatobiliary diseases and contribute to cholangiocarcinoma  ...[more]

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