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Quantitative proteomic analysis of the hemolymph from Bithynia siamensis goniomphalos infected with Opisthorchis viverrini

ABSTRACT: We have performed a quantitative proteomic analysis of the hemocytes and plasma proteins from O. viverrini-infected Bithynia siamensis goniomphalos snails using SWATH-MS. The dataset contains validation SWATH-MS data and Skyline results plus the sample-specific libraries.

INSTRUMENT(S): TripleTOF 5600

ORGANISM(S): Bithynia Siamensis Goniomphalos

TISSUE(S): Hemolymph

SUBMITTER: Javier Sotillo

LAB HEAD: Alex Loukas

PROVIDER: PXD004121 | Pride | 2016-10-17

REPOSITORIES: Pride

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Differential Protein Expression in the Hemolymph of Bithynia siamensis goniomphalos Infected with Opisthorchis viverrini.

Suwannatrai Kulwadee K Suwannatrai Apiporn A Tabsripair Pairat P Welbat Jariya Umka JU Tangkawattana Sirikachorn S Cantacessi Cinzia C Mulvenna Jason J Tesana Smarn S Loukas Alex A Sotillo Javier J

PLoS neglected tropical diseases 20161128 11

Bithynia siamensis goniomphalos is a freshwater snail that serves as the first intermediate host of the human liver fluke Opisthorchis viverrini. This parasite is a major public health problem in different countries throughout the Greater Mekong sub-region (Thailand, southern Vietnam, Lao PDR and Cambodia). Chronic O. viverrini infection also results in a gradual increase of fibrotic tissues in the biliary tract that are associated with hepatobiliary diseases and contribute to cholangiocarcinoma ...[more]

PMID: 27893749

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