Allele-Specific Protein Abundance in Human Brain

ABSTRACT: We describe a method for identifying peptides that result from missense changes and identify peptides among 2 human brains that would have otherwise not been detected. Next, we use this data to estimate of allele-specific protein abundance in human brain for an average per individual, and to estimate apolipoprotein E allele specific abundance in human brain across individuals. Finally, we estimate the heritability of allele-specific protein abundance.

INSTRUMENT(S):

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Brain

SUBMITTER: Duc Duong  

LAB HEAD: NIcholas Seyfried

PROVIDER: PXD004143 | Pride | 2017-07-31

REPOSITORIES: Pride