Dataset Information
Proteomic analysis of mucus from chronic rhinosinusitis patients with or without nasal polyps
Ontology highlight
ABSTRACT:
INSTRUMENT(S):
ORGANISM(S): Homo Sapiens (human)
SUBMITTER: 
Benjamin Neely
LAB HEAD: Richard R. Drake
PROVIDER: PXD004144 | Pride | 2016-05-26
REPOSITORIES: Pride
Dataset's files
| Action | DRS | |||
|---|---|---|---|---|
| 05292014_Mucus-02-1 - F002343.pride.mztab.gz | Mztab | |||
| 05292014_Mucus-02-1-F002343.dat | Other | |||
| 05292014_Mucus-02-1-F002343.mzid.gz | Mzid | |||
| 05292014_Mucus-02-1.RAW | Raw | |||
| 05292014_Mucus-02-1.mgf | Mgf |
Items per page: 1 - 5 of 73 |
Publications
Role of C3a as a Novel Regulator of 25(OH)D<sub>3</sub> to 1α,25-Dihydroxyvitamin D<sub>3</sub> Metabolism in Upper Airway Epithelial Cells.
Journal of immunology (Baltimore, Md. : 1950) 20220706 2
In patients with chronic rhinosinusitis with nasal polyps, primary human sinonasal epithelial cell (HSNEC) 1α-hydroxylase levels are reduced, as is their ability to metabolize 25-hydroxycholecalciferol [25(OH)D<sub>3</sub>] to its active metabolite, 1α,25-dihydroxyvitamin D<sub>3</sub> [1,25(OH)<sub>2</sub>D<sub>3</sub>]. In this study, we sought to identify the factor responsible for the regulation of HSNEC metabolism of 25(OH)D<sub>3</sub>, focusing on C3 and C3a. Multiple inhaled irritants tr ...[more]
