Proteomic Time-Course Investigation into the Effects of Exposure of Mycobacterium smegmatis to Sub-Lethal Dose of Rifampicin

ABSTRACT: Drug susceptible Mycobacterium smegmatis (Mc2-155) was exposed to a sub-MIC concentration of antimycobacterial drug Rifampicin (treated) or DMSO (control). Cells were harvested at 30, 255 and 300 minutes post-exposure and the proteome at each time analysed using LC-MS/MS on a Thermo Q-Exactive.

INSTRUMENT(S):

ORGANISM(S): Mycobacterium Smegmatis (strain Atcc 700084 / Mc(2)155)

DISEASE(S): Tuberculosis

SUBMITTER: Alexander Giddey  

LAB HEAD: Jonathan M Blackburn

PROVIDER: PXD004197 | Pride | 2017-03-15

REPOSITORIES: Pride