Proteomic and bioinformatic characterization of extracellular vesicles released from human primary macrophages upon influenza A infection

ABSTRACT: We have previously shown that IAV infection of human monocyte-derived macrophages causes major alterations to subcellular protein trafficking inside the cell and triggers robust protein secretion (Lietzén et al, 2011). Here, we have used high-throughput proteomics to identify proteins secreted in extracellular vesicles (EVs) during influenza A virus infection of human macrophages.

INSTRUMENT(S):

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Cell Culture, Macrophage

DISEASE(S): Influenza

SUBMITTER: Tuula Nyman  

LAB HEAD: Tuula Anneli Nyman

PROVIDER: PXD004424 | Pride | 2017-02-07

REPOSITORIES: Pride