Ontology highlight
ABSTRACT:
INSTRUMENT(S): Q Exactive
ORGANISM(S): Homo Sapiens (human)
TISSUE(S): Epithelial Cell, Cell Culture
DISEASE(S): Respiratory Syncytial Virus Infectious Disease
SUBMITTER: Stuart Armstrong
LAB HEAD: Julian Hiscox
PROVIDER: PXD004430 | Pride | 2022-03-01
REPOSITORIES: Pride
Molecular & cellular proteomics : MCP 20200219 5
The respiratory epithelium comprises polarized cells at the interface between the environment and airway tissues. Polarized apical and basolateral protein secretions are a feature of airway epithelium homeostasis. Human respiratory syncytial virus (hRSV) is a major human pathogen that primarily targets the respiratory epithelium. However, the consequences of hRSV infection on epithelium secretome polarity and content remain poorly understood. To investigate the hRSV-associated apical and basolat ...[more]