Multiple sclerosis biomarker discovery in cerebrospinal fluid using glycopeptide enrichment, TMT labeling and LC-MS/MS

ABSTRACT: Multiple sclerosis biomarker discovery in pooled cerebrospinal fluid (CSF) using glycopeptide enrichment, TMT labeling and LC-MS/MS. Comparing 3 pools of CSF from relapsing-remitting MS (RRMS) patients to 3 pools of CSF from patients with other neurological diseases (OND). To reveal protein groups and networks affected by MS and to look at correlation between a glyco and a global approach.

INSTRUMENT(S):

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Cerebrospinal Fluid

DISEASE(S): Multiple Sclerosis

SUBMITTER: Astrid Guldbrandsen  

LAB HEAD: Frode S. Berven

PROVIDER: PXD004540 | Pride | 2016-10-13

REPOSITORIES: Pride