Proteomics

Dataset Information

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In-depth analysis of the phosphoprotein landscape of cytotoxic T lymphocytes and its regulation by cytokines


ABSTRACT: Here we present high-resolution mass spectrometry analysis of changes to the phosphoproteome of cytotoxic T lymphocytes (CTL) induced by the cytokine, Interleukin 12 (IL-12). We treated CTL with a short and long IL-12 stimulation and mapped the changes to the phosphoproteome using quantitative SILAC-based phosphoproteomics.

INSTRUMENT(S): LTQ Orbitrap Velos

ORGANISM(S): Mus Musculus (mouse)

TISSUE(S): Spleen, Cd8-positive, T Cell

SUBMITTER: Sarah Ross  

LAB HEAD: Doreen Ann Cantrell

PROVIDER: PXD004644 | Pride | 2016-08-24

REPOSITORIES: Pride

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