Chemical proteomics to elucidate target proteins of cysteine-stabilized and circular peptides

ABSTRACT: Cyclotides are circular and cystine-rich peptides which are little amenable to chemical modifications for probe design in chemical biology. The cyclotide [T20K]kalata B1 is an immune system modulating drug reported for its therapeutic application in multiple sclerosis.

INSTRUMENT(S):

ORGANISM(S): Homo Sapiens (human) Mus Musculus (mouse)

TISSUE(S): Spleen, T Cell, Jurkat Cell

SUBMITTER: Roland Hellinger  

LAB HEAD: Christian Werner Gruber

PROVIDER: PXD004798 | Pride | 2017-09-26

REPOSITORIES: Pride