Ontology highlight
ABSTRACT:
INSTRUMENT(S): Q Exactive
ORGANISM(S): Mus Musculus (mouse)
TISSUE(S): Cell Culture
DISEASE(S): Neuroblastoma
SUBMITTER: Yongbo Wang
LAB HEAD: Yu Xue
PROVIDER: PXD004891 | Pride | 2018-10-26
REPOSITORIES: Pride
Chen Lei-Lei LL Wang Yong-Bo YB Song Ju-Xian JX Deng Wan-Kun WK Lu Jia-Hong JH Ma Li-Li LL Yang Chuan-Bin CB Li Min M Xue Yu Y
Autophagy 20171004 11
Recent studies have demonstrated that dysregulation of macroautophagy/autophagy may play a central role in the pathogenesis of neurodegenerative disorders, and the induction of autophagy protects against the toxic insults of aggregate-prone proteins by enhancing their clearance. Thus, autophagy has become a promising therapeutic target against neurodegenerative diseases. In this study, quantitative phosphoproteomic profiling together with a computational analysis was performed to delineate the p ...[more]