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Comparative evaluation of the aqueous humor proteome of primary angle closure and primary open angle glaucomas and senile cataract eyes

ABSTRACT: Comparative evaluation of the aqueous humor proteome of primary angle closure and primary open angle glaucomas and senile cataract eyes

INSTRUMENT(S): LTQ Orbitrap Velos

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Anterior Chamber Of The Eye

SUBMITTER: Inderjeet Kaur

LAB HEAD: Ramanjit Sihota

PROVIDER: PXD004928 | Pride | 2020-05-29

REPOSITORIES: Pride

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			Action	DRS
	Cat_1_U_R.raw	Raw
	Cat_1_U_R_long.raw	Raw
	Cat_1_U_R_long2.raw	Raw
	Cat_2_long1.raw	Raw
	Cat_2_long2.raw	Raw

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Comparative evaluation of the aqueous humor proteome of primary angle closure and primary open angle glaucomas and age-related cataract eyes.

Kaur Inderjeet I Kaur Jasbir J Sooraj K K Goswami Sandeep S Saxena Rohit R Chauhan Virander Singh VS Sihota Ramanjit R

International ophthalmology 20180113 1

<h4>Purpose</h4>To analyze and compare the total proteome of aqueous humor (AH) from patients having primary angle closure glaucoma (PACG), primary open angle glaucoma (POAG) and age-related cataract.<h4>Materials and methodology</h4>Aqueous humor was collected from age-matched PACG, POAG and cataract patients who underwent surgery, and it was immediately stored at - 80 °C until analysis. From each sample, 25 µg of total protein was subjected to trypsin digestion and subsequently LC-MS/MS analys ...[more]

PMID: 29332228

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