Lapatinib action and resistance in breast cancer
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ABSTRACT: We used an established cell line model of lapatinib resistance and employed explorative mass spectrometry to profile the proteome, kinome and phosphoproteome changes in an effort to systematically investigate initial inhibitor response and concomitant kinome reprogramming and signaling rewiring in resistance. Experiments were performed in three biological replicates
INSTRUMENT(S): Q Exactive
ORGANISM(S): Homo Sapiens (human)
DISEASE(S): Breast Cancer
SUBMITTER: Benjamin Ruprecht
LAB HEAD: Simone Lemeer
PROVIDER: PXD004981 | Pride | 2017-02-27
REPOSITORIES: Pride
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