Proteomics

Dataset Information

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DREX proteome analysis for spectral library

ABSTRACT: In order to prepare a spectral library for data-indepentend acquisition mass spectrometry studies, we try to cover as many proteins from Drosophila melanogaster embryonic protein extracts.

INSTRUMENT(S): TripleTOF 6600

ORGANISM(S): Drosophila Melanogaster (fruit Fly)

TISSUE(S): Embryo, Early Embryonic Cell

SUBMITTER: Andreas Schmidt  

LAB HEAD: Axel Imhof

PROVIDER: PXD005100 | Pride | 2019-02-25

REPOSITORIES: Pride

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Publications

A Quantitative Proteomic Analysis of In Vitro Assembled Chromatin.

Völker-Albert Moritz Carl MC   Pusch Miriam Caroline MC   Fedisch Andreas A   Schilcher Pierre P   Schmidt Andreas A   Imhof Axel A  

Molecular & cellular proteomics : MCP 20160125 3

The structure of chromatin is critical for many aspects of cellular physiology and is considered to be the primary medium to store epigenetic information. It is defined by the histone molecules that constitute the nucleosome, the positioning of the nucleosomes along the DNA and the non-histone proteins that associate with it. These factors help to establish and maintain a largely DNA sequence-independent but surprisingly stable structure. Chromatin is extensively disassembled and reassembled dur  ...[more]

PMID: 26811354

Publication: 1/2

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