Comparative secretome analysis after particulate exposure in human lung cell culture models

ABSTRACT: 2D (A549) and 3D (AIR-606) human lung epithelial cell cultures were mock treated or exposed to 100 ug/ml petroleum coke or urban air particulates (both in the PM10 range) for 16 h. Secretomes were compared for triplicate treatments for each group by isobaric tags and LC/MS/MS.

INSTRUMENT(S):

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Lung, Epithelial Cell

DISEASE(S): Pulmonary Fibrosis

SUBMITTER: Joseph Caruso  

LAB HEAD: Dr. Paul Stemmer

PROVIDER: PXD005194 | Pride | 2018-03-26

REPOSITORIES: Pride