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Immunomodulation by mung bean

ABSTRACT: The immunomodulatory effect of mung bean is mainly attributed to antioxidant properties of flavonoids; however, the precise machinery for biological effect on animal cells remains uncertain. The objective of this study was to understand the physiological change produced by mung bean consumption.

INSTRUMENT(S): LTQ Orbitrap

ORGANISM(S): Mus Musculus (mouse)

TISSUE(S): Macrophage

SUBMITTER: Akiko Hashiguchi

LAB HEAD: Setsuko Komatsu

PROVIDER: PXD005330 | Pride | 2017-04-06

REPOSITORIES: Pride

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Mung bean (Vigna radiata (L.)) coat extract modulates macrophage functions to enhance antigen presentation: A proteomic study.

Hashiguchi Akiko A Hitachi Keisuke K Zhu Wei W Tian Jingkui J Tsuchida Kunihiro K Komatsu Setsuko S

Journal of proteomics 20170331

The immunomodulatory effect of mung bean is mainly attributed to antioxidant properties of flavonoids; however, the precise machinery for biological effect on animal cells remains uncertain. To understand the physiological change produced by mung bean consumption, proteomic and metabolomic techniques were used. In vitro assay confirmed the importance of synergistic interaction among multiple flavonoids by IL-6 expression. Proteomic analysis detected that the abundance of 190 proteins was changed ...[more]

PMID: 28373035

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