MEIOC interacting proteins during meiotic prophase I

ABSTRACT: The meiosis-specific chromosomal events of homolog pairing, synapsis, and recombination occur over an extended meiotic prophase I. In this study, we show that, in mice, maintenance of an extended meiotic prophase I requires the gene Meioc, a germ-cell specific factor conserved in most metazoans. Using immunoprecipitation and quantitative mass spectrometry, we identify proteins that interact with MEIOC in the mouse germ line.

OTHER RELATED OMICS DATASETS IN: PRJNA380166 PRJNA355552 GSE90702

INSTRUMENT(S):

ORGANISM(S): Mus Musculus (mouse)

TISSUE(S): Epithelial Cell

SUBMITTER: Amanda Del Rosario  

LAB HEAD: Amanda Del Rosario

PROVIDER: PXD005473 | Pride | 2017-03-27

REPOSITORIES: Pride