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Proteomics of C. briggsae embryo and larvae

ABSTRACT: To gain mechanistic insights into the molecular changes of Caenorhabditis briggsae between the two developmental stages: embryo and larvae

INSTRUMENT(S): TripleTOF 5600

ORGANISM(S): Caenorhabditis Elegans

TISSUE(S): Embryo, Fibroblast

DISEASE(S): Disease Free

SUBMITTER: Huoming Zhang

LAB HEAD: Zhongying Zhao

PROVIDER: PXD005549 | Pride | 2018-10-11

REPOSITORIES: Pride

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Comparative proteome analysis between C . briggsae embryos and larvae reveals a role of chromatin modification proteins in embryonic cell division.

An Xiaomeng X Shao Jiaofang J Zhang Huoming H Ren Xiaoliang X Ho Vincy Wing Sze VWS Li Runsheng R Wong Ming-Kin MK Zhao Zhongying Z

Scientific reports 20170627 1

Caenorhabditis briggsae has emerged as a model for comparative biology against model organism C. elegans. Most of its cell fate specifications are completed during embryogenesis whereas its cell growth is achieved mainly in larval stages. The molecular mechanism underlying the drastic developmental changes is poorly understood. To gain insights into the molecular changes between the two stages, we compared the proteomes between the two stages using iTRAQ. We identified a total of 2,791 proteins ...[more]

PMID: 28655887

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