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Deep gut metaproteomics - A deep metaproteomics approach for the study of human microbiomes

ABSTRACT: Stool samples were collected from 4 children and subjected to deep gut metaproteomics analysis for in-depth understanding the functional compositions of human gut mcirobiome.

INSTRUMENT(S): Q Exactive

ORGANISM(S): Human Gut Metagenome

SUBMITTER: Xu Zhang

LAB HEAD: Daniel Figeys

PROVIDER: PXD005619 | Pride | 2017-08-10

REPOSITORIES: Pride

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Deep Metaproteomics Approach for the Study of Human Microbiomes.

Zhang Xu X Chen Wendong W Ning Zhibin Z Mayne Janice J Mack David D Stintzi Alain A Tian Ruijun R Figeys Daniel D

Analytical chemistry 20170811 17

Host-microbiome interactions have been shown to play important roles in human health and diseases. Most of the current studies of the microbiome have been performed by genomic approaches through next-generation sequencing. Technologies, such as metaproteomics, for functional analysis of the microbiome are needed to better understand the intricate host-microbiome interactions. However, significant efforts to improve the depth and resolution of gut metaproteomics are still required. In this study, ...[more]

PMID: 28749657

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