Proteomics

Dataset Information

42

Mouse female gonad quantitative MS


ABSTRACT: We constructed a comparative proteome profile of female mouse fetal gonads at specific time points (11.5, 12.5, and 13.5 days post coitum), spanning a critical window for initiation of meiosis in female germ cells. We identified 3666 proteins, of which 473 were differentially expressed.

INSTRUMENT(S): LTQ Orbitrap Velos

ORGANISM(S): Mus musculus  

TISSUE(S): Gonad

DISEASE(S): Not Available

SUBMITTER: hao zhang  

LAB HEAD: Ran Huo

PROVIDER: PXD005670 | Pride | 2017-11-27

REPOSITORIES: Pride

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Publications

A Comparative Proteome Profile of Female Mouse Gonads Suggests a Tight Link between the Electron Transport Chain and Meiosis Initiation.

Shen Cong C   Li Mingrui M   Zhang Pan P   Guo Yueshuai Y   Zhang Hao H   Zheng Bo B   Teng Hui H   Zhou Tao T   Guo Xuejiang X   Huo Ran R  

Molecular & cellular proteomics : MCP 20171120 1


Generation of haploid gametes by meiosis is a unique property of germ cells and is critical for sexual reproduction. Leaving mitosis and entering meiosis is a key step in germ cell development. Several inducers or intrinsic genes are known to be important for meiotic initiation, but the regulation of meiotic initiation, especially at the protein level, is still not well understood. We constructed a comparative proteome profile of female mouse fetal gonads at specific time points (11.5, 12.5, and  ...[more]

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