Ontology highlight
ABSTRACT:
INSTRUMENT(S): LTQ Orbitrap Elite
ORGANISM(S): Trypanosoma Brucei
SUBMITTER: Friedel Drepper
LAB HEAD: Prof. Dr. Bettina Warscheid
PROVIDER: PXD005725 | Pride | 2017-06-14
REPOSITORIES: Pride
Nature communications 20170509
Protein import into organelles is essential for all eukaryotes and facilitated by multi-protein translocation machineries. Analysing whether a protein is transported into an organelle is largely restricted to single constituents. This renders knowledge about imported proteins incomplete, limiting our understanding of organellar biogenesis and function. Here we introduce a method that enables charting an organelle's importome. The approach relies on inducible RNAi-mediated knockdown of an essenti ...[more]