Human serum proteome dynamics in type 2 diabetes using heavy water labeling mass spectrometry

ABSTRACT: Control subjects and type 2 diabetic patients were given deuterium-labeled (heavy) water for a seven-day period and their plasma serum proteins were analyzed by high-resolution mass spectrometry. Using an in-house-developed software, fractional synthesis rates were calculated for proteins of interest. These data can be used for qualitative, quantitative, and kinetics study of human serum proteins under healthy and type 2 diabetes conditions.

INSTRUMENT(S):

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Blood Plasma

DISEASE(S): Type 2 Diabetes Mellitus

SUBMITTER: Takhar Kasumov  

LAB HEAD: Takhar Kasumov

PROVIDER: PXD005755 | Pride | 2017-11-02

REPOSITORIES: Pride