Ontology highlight
ABSTRACT:
INSTRUMENT(S): LTQ Orbitrap Elite
ORGANISM(S): Homo Sapiens (human)
TISSUE(S): Blood Plasma
DISEASE(S): Liver Cirrhosis,Hepatitis C,Hepatocellular Carcinoma
SUBMITTER: Thilo Bracht
LAB HEAD: Barbara Sitek
PROVIDER: PXD005777 | Pride | 2017-06-21
REPOSITORIES: Pride
Proteomics. Clinical applications 20170710 11-12
<h4>Purpose</h4>Hepatocellular carcinoma (HCC) is the most common primary malignant liver tumor and a leading cause of cancer-related deaths worldwide. Cirrhosis induced by hepatitis-C virus (HCV) infection is the most critical risk factor for HCC. However, the mechanism of HCV-induced carcinogenesis is not fully understood. Plasma microparticles (PMP) contribute to numerous physiological and pathological processes and contain proteins whose composition correlates to the respective pathophysiolo ...[more]