Proteomics,Multiomics

Dataset Information

0

Striatal and hippocampal astrocyte proteomes


ABSTRACT: We quantitavely compared striatal and hippocampal astrocyte proteomes using stable-isotopic dimethyl labeling.

OTHER RELATED OMICS DATASETS IN: PRJNA363047

INSTRUMENT(S): LTQ Orbitrap

ORGANISM(S): Mus Musculus (mouse)

TISSUE(S): Brain, T Cell, Astrocyte

SUBMITTER: Blanca Diaz Castro  

LAB HEAD: Baljit S. Khakh

PROVIDER: PXD005852 | Pride | 2017-07-10

REPOSITORIES: Pride

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Publications


Astrocytes are ubiquitous in the brain and are widely held to be largely identical. However, this view has not been fully tested, and the possibility that astrocytes are neural circuit specialized remains largely unexplored. Here, we used multiple integrated approaches, including RNA sequencing (RNA-seq), mass spectrometry, electrophysiology, immunohistochemistry, serial block-face-scanning electron microscopy, morphological reconstructions, pharmacogenetics, and diffusible dye, calcium, and glu  ...[more]

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