Investigating Reporter Ion Signal Characteristics in Isobaric Mass Tag Proteome Quantification Experiments

ABSTRACT: In this study we sought to examine the characteristics of the reporter ion signal obtained using current generation OT-based MS hardware. We initially focus on re-analysis of a previous experiment where TMT was using in combination with OT-MS3 to study protein expression diversity between histotypes of ovarian carcinoma where the presence of a notch – a region with no reported values – was observed in the reporter ion signal distributions.

INSTRUMENT(S):

ORGANISM(S): Yarrowia Lipolytica (candida Lipolytica) Homo Sapiens (human) Ralstonia Eutropha Jmp134

SUBMITTER: Christopher Hughes  

LAB HEAD: Gregg Morin

PROVIDER: PXD005892 | Pride | 2017-04-26

REPOSITORIES: Pride