Delineating changing partners of Akt1 protein as a function of its active state in HEK-293 Cells
Ontology highlight
ABSTRACT:
INSTRUMENT(S): TripleTOF 5600
ORGANISM(S): Homo Sapiens (human)
TISSUE(S): Cell Culture
SUBMITTER: 
Shweta Duggal
LAB HEAD: Dr. Kanury V.S. Rao
PROVIDER: PXD005976 | Pride | 2017-03-02
REPOSITORIES: Pride
Publications
Dataset to delineate changes in association between Akt1 and its interacting partners as a function of active state of Akt1 protein.
Gupta Nutan N Duggal Shweta S Jailkhani Noor N Chatterjee Samrat S Rao Kanury V S KVS Kumar Ajay A
Data in brief 20170525
Akt1 is a multi-functional protein, implicated in multiple human solid tumors. Pertaining to its key role in cell survival, Akt1 is under focus for development of targeted therapies. Functional diversity of Akt1 is a result of its interactions with other proteins; which changes with changing context. This investigation was designed to capture the dynamics of Akt1 Interactome as a function of its active state. Delineating dynamic changes in association of Akt1 with its interactors could help us c ...[more]
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