Post-translational modifications of vaccine candidates of Cryptosporidium parvum

ABSTRACT: Here we describe the post translational modifications on vaccine candidate proteins from Cryptosporidium parvum. We have identified O-glycosylated peptides from GP15, GP40, GP900, and a novel mucin-like protein referred to as GP20. In addition, we have discovered that the immune dominant antigen, CP23, contains both N-myristoyl and C-palmitoyl modifications on the N-terminal region of the protein.

INSTRUMENT(S):

ORGANISM(S): Cryptosporidium Parvum

TISSUE(S): Sporulated Oocyst

SUBMITTER: John Haserick  

LAB HEAD: Catherine E. Costello

PROVIDER: PXD005989 | Pride | 2017-08-14

REPOSITORIES: Pride