Multi-omics analysis of β-catenin oncogenic networks

ABSTRACT: We used interaction and expression proteomic techniques in conjunction with RNA-Seq transcriptomic analysis to analyse how a β-catenin stabilizing mutation alters molecular networks in colorectal cancer cells. Integrated computational analyses of allowed us to identify significantly altered sub-networks linked to β-catenin oncogenesis.

INSTRUMENT(S):

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Epithelial Cell, Cell Culture

DISEASE(S): Colon Cancer

SUBMITTER: Rob Ewing  

LAB HEAD: Rob Ewing

PROVIDER: PXD006053 | Pride | 2018-05-18

REPOSITORIES: Pride