Proteomics

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Proteomics on post-mortem human brain tissue of patients with Alzheimer`s, Parkinson`s and Lewy body dementias.

ABSTRACT: We have used HiRIEF (High Resolution Isoelectric Focusing) LC-MS proteomics with isobaric tags (TMT10plex) to compare 32 post-mortem human brains in the prefrontal cortex (Brodmann area 9) of prospectively followed patients with Alzheimer`s disease (AD), Parkinson`s disease with dementia (PDD), dementia with Lewy bodies (DLB) and older adults without dementia.

INSTRUMENT(S):

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Brain

DISEASE(S): Lewy Body Dementia,Alzheimer's Disease,Parkinson's Disease

SUBMITTER: Rui Branca  

LAB HEAD: Janne Lehtiö

PROVIDER: PXD006122 | Pride | 2017-12-08

REPOSITORIES: Pride

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Dataset's files

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Action DRS
Rui_Erika_Synaptic_Proteomics_BA9_TMTset1_250ug_IPG3-10_50min_10of15ul_fr01-72_seq-phos_uniprot.msf Msf
Rui_Erika_Synaptic_Proteomics_BA9_TMTset1_250ug_IPG3-10_50min_10of15ul_fr01.raw Raw
Rui_Erika_Synaptic_Proteomics_BA9_TMTset1_250ug_IPG3-10_50min_10of15ul_fr02.raw Raw
Rui_Erika_Synaptic_Proteomics_BA9_TMTset1_250ug_IPG3-10_50min_10of15ul_fr03.raw Raw
Rui_Erika_Synaptic_Proteomics_BA9_TMTset1_250ug_IPG3-10_50min_10of15ul_fr04.raw Raw
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