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Proteomics Reveal Global Regulation of Protein SUMOylation by ATM and ATR Kinases during Replication Stress

ABSTRACT: The mechanisms that protect eukaryotic DNA duringdepend on several post-translational modifications (PTMs)-based signaling pathways. Phosphorylation is a well-known regulator of the replication stress response Here we investigate the global interplay between phosphorylation and SUMOylation in response to replication stress.

INSTRUMENT(S): Q Exactive

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Bone Marrow

SUBMITTER: Stephanie Munk

LAB HEAD: Jesper V. Olsen

PROVIDER: PXD006361 | Pride | 2017-10-09

REPOSITORIES: Pride

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