Proteomic analysis to investigate lung injury in a mouse model of Streptococcus pneumonia infection
Ontology highlight
ABSTRACT:
INSTRUMENT(S): ultraflex
ORGANISM(S): Mus Musculus (mouse)
TISSUE(S): Lung
DISEASE(S): Pneumonia
SUBMITTER: 
MARIO Ferrer-Navarro
LAB HEAD: Jordi Vila
PROVIDER: PXD006393 | Pride | 2018-06-10
REPOSITORIES: Pride
Publications
Changed Expression of Cytoskeleton Proteins During Lung Injury in a Mouse Model of <i>Streptococcus pneumoniae</i> Infection.
Ferrer-Navarro Mario M Strehlitz Anja A Medina Eva E Vila Jordi J
Frontiers in microbiology 20180508
Infections by <i>Streptococcus pneumoniae</i> are a major cause of morbidity and mortality worldwide, often causing community-acquired pneumonia, otitis media and also bacteremia and meningitis. Studies on <i>S. pneumoniae</i> are mainly focused on its virulence or capacity to evade the host immune system, but little is known about the injury caused in lungs during a pneumococcal infection. Herein we investigated this issue comparing the proteome profile of lungs from <i>S. pneumoniae-</i>infect ...[more]
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