HLA-C*05:01 and HLA-C*07:02 from 721.221 cells

ABSTRACT: HLA-C expresion varies widely across the different HLA-C alleles. MicroRNA binding can partly explain the differences in HLA-C allele expression however other contributing factors still remain undetermined. Here we use two common HLA-C alleles, HLA-C*05:01 and HLA-C*07:02, to explore differences in expression levels. Using functional, structural and peptide repertoire comparisons we demonstrate that HLA-C expression levels are not only modulated at the RNA level but also at the protein level. This dataset contains RAW data and database search results for HLA-C*05:01 and HLA-C*07:02 from the 721.221 cell line.

INSTRUMENT(S):

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Leukocyte, Cell Culture

SUBMITTER: Jesse Mobbs  

LAB HEAD: Anthony W Purcell

PROVIDER: PXD006455 | Pride | 2017-07-03

REPOSITORIES: Pride