Proteomics

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Proteogenomic Re-annotation of Coccidioides posadasii strain Silveira


ABSTRACT: The aims of this study were to present modifications to the annotations of the genome of C. posadasii, one of two closely related species of Coccidioides, a dimorphic fungal pathogen that causes coccidioidomycosis, also called Valley Fever. Proteins present in lysates and filtrates of in vitro grown mycelia and parasitic phase spherules from C. posadasii strain Silveira were analyzed using a GeLC-MS/MS method.

INSTRUMENT(S): Q Exactive

ORGANISM(S): Coccidioides Posadasii Str. Silveira

DISEASE(S): Coccidioidomycosis

SUBMITTER: Natalie Mitchell  

LAB HEAD: Douglas F Lake

PROVIDER: PXD006489 | Pride | 2017-11-08

REPOSITORIES: Pride

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Publications

Proteogenomic Re-Annotation of Coccidioides posadasii Strain Silveira.

Mitchell Natalie M NM   Sherrard Andrew L AL   Dasari Surendra S   Magee D Mitchell DM   Grys Thomas E TE   Lake Douglas F DF  

Proteomics 20171214 1


The aims of this study are to provide protein-based evidence upon which to reannotate the genome of Coccidiodes posadasii, one of two closely related species of Coccidioides, a dimorphic fungal pathogen that causes coccidioidomycosis, also called Valley fever. Proteins present in lysates and filtrates of in vitro grown mycelia and parasitic phase spherules from C. posadasii strain Silveira are analyzed using a GeLC-MS/MS method. Acquired spectra are processed with a proteogenomics workflow compr  ...[more]

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