Ontology highlight
ABSTRACT:
INSTRUMENT(S): Q Exactive
ORGANISM(S): Homo Sapiens (human)
TISSUE(S): Urinary Bladder
DISEASE(S): Bladder Transitional Cell Carcinoma
SUBMITTER: Dohyun Han
LAB HEAD: Dohyun Han
PROVIDER: PXD006805 | Pride | 2018-07-04
REPOSITORIES: Pride
Molecular & cellular proteomics : MCP 20180627 9
Cytological examination of urine is the most widely used noninvasive pathologic screen for bladder urothelial carcinoma (BLCA); however, inadequate diagnostic accuracy remains a major challenge. We performed mass spectrometry-based proteomic analysis of urine samples of ten patients with BLCA and ten paired patients with benign urothelial lesion (BUL) to identify ancillary proteomic markers for use in liquid-based cytology (LBC). A total of 4,839 proteins were identified and 112 proteins were co ...[more]