Ontology highlight
ABSTRACT:
INSTRUMENT(S): Q Exactive
ORGANISM(S): Escherichia Coli
SUBMITTER: Chiara guerrera
LAB HEAD: Chiara Guerrera
PROVIDER: PXD006908 | Pride | 2018-11-22
REPOSITORIES: Pride
Ziveri Jason J Tros Fabiola F Guerrera Ida Chiara IC Chhuon Cerina C Audry Mathilde M Dupuis Marion M Barel Monique M Korniotis Sarantis S Fillatreau Simon S Gales Lara L Cahoreau Edern E Charbit Alain A
Nature communications 20171011 1
The enzyme fructose-bisphosphate aldolase occupies a central position in glycolysis and gluconeogenesis pathways. Beyond its housekeeping role in metabolism, fructose-bisphosphate aldolase has been involved in additional functions and is considered as a potential target for drug development against pathogenic bacteria. Here, we address the role of fructose-bisphosphate aldolase in the bacterial pathogen Francisella novicida. We demonstrate that fructose-bisphosphate aldolase is important for bac ...[more]