Proteomics

Dataset Information

Human Mitochondria NFS1-ISCU-FXN XL-MS

ABSTRACT: Frataxin (FXN) is involved in mitochondrial iron-sulfur (Fe-S) cluster biogenesis and serves to accelerate Fe-S cluster formation. FXN deficiency is associated with Friedreich ataxia, a neurodegenerative disease. Using chemical cross-linking (XL) accompanied with LC-MS/MS, we studied the the interaction between the core complexes Acp-ISD11-NFS1 (AIN) and AIN-ISCU (AINU) with FXN.

INSTRUMENT(S):

ORGANISM(S): Homo Sapiens (human)

DISEASE(S): Friedreich Ataxia

SUBMITTER: Kai Cai  

LAB HEAD: John L. Markley

PROVIDER: PXD006938 | Pride | 2018-07-11

REPOSITORIES: Pride

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Dataset's files

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Action DRS
2_NFS1-Fxn-IscU_Markley (F016506).mzid_2_NFS1-Fxn-IscU_Markley_(F016506).pride.mgf.gz Mzid
2_NFS1-Fxn-IscU_Markley (F016506).pride.mztab.gz Mztab
2_NFS1-Fxn-IscU_Markley.raw Raw
2_NFS1-Fxn-IscU_Markley.zhrs Other
2_NFS1-Fxn-IscU_MarkleyF016506.mzid.gz Mzid
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