Ontology highlight
ABSTRACT:
INSTRUMENT(S): LTQ Orbitrap Velos
ORGANISM(S): Rattus Norvegicus (rat)
TISSUE(S): Pancreas
DISEASE(S): Acute Pancreatitis
SUBMITTER: Violeta García-Hernández
LAB HEAD: Jesús Sánchez-Yagüe
PROVIDER: PXD007096 | Pride | 2018-05-22
REPOSITORIES: Pride
García-Hernández Violeta V Sánchez-Bernal Carmen C Schvartz Domitille D Calvo José J JJ Sanchez Jean-Charles JC Sánchez-Yagüe Jesús J
Journal of proteomics 20180417
Changes in the protein expression occurring within the initiation phase of acute pancreatitis (AP) might be vital in the development of this complex disease. However, the exact mechanisms involved in the onset of AP remains elusive and most of our knowledge about the pathobiology of AP comes from animal models. We performed in a rat pancreatitic model a high-throughput shotgun proteomic profiling of the soluble and whole membrane fractions from the pancreas during the early phase of cerulein (Ce ...[more]