Abl subtrates using tyrosine phosphoproteomics

ABSTRACT: In this study, we have prepared a mouse embryonic fibrobalst (MEF) cell line stably expressing R367A mutant human Abl in which the native mouse Abl1 and Abl2 were genetically deleted. We have used these R367A mutant Abl cells in combination with mass spectrometry to identify phosphorylation targets of Abl. Below, we describe these findings and their potential biological significance.

INSTRUMENT(S):

ORGANISM(S): Mus Musculus (mouse)

TISSUE(S): Cell Culture, Fibroblast

DISEASE(S): Disease Free

SUBMITTER: Min-Sik Kim  

LAB HEAD: Min-Sik Kim

PROVIDER: PXD007118 | Pride | 2018-03-16

REPOSITORIES: Pride