Ontology highlight
ABSTRACT:
INSTRUMENT(S): Q Exactive
ORGANISM(S): Saccharomyces Cerevisiae (baker's Yeast)
SUBMITTER: Kristina Poljak
LAB HEAD: Markus Aebi
PROVIDER: PXD007215 | Pride | 2017-11-03
REPOSITORIES: Pride
Poljak Kristina K Breitling Jörg J Gauss Robert R Rugarabamu George G Pellanda Mauro M Aebi Markus M
The Journal of biological chemistry 20171017 49
<i>N</i>-Linked protein glycosylation is an essential and highly conserved post-translational modification in eukaryotes. The transfer of a glycan from a lipid-linked oligosaccharide (LLO) donor to the asparagine residue of a nascent polypeptide chain is catalyzed by an oligosaccharyltransferase (OST) in the lumen of the endoplasmic reticulum (ER). <i>Trypanosoma brucei</i> encodes three paralogue single-protein OSTs called <i>Tb</i>STT3A, <i>Tb</i>STT3B, and <i>Tb</i>STT3C that can functionally ...[more]