Proteomics

Dataset Information

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Phosphoproteomic study of TOR inhibition in Chlamydomonas reinhardtii


ABSTRACT: For further details, please refer to the publication.

INSTRUMENT(S): TripleTOF 5600

ORGANISM(S): Chlamydomonas Reinhardtii

TISSUE(S): Photosynthetic Cell

SUBMITTER: Evan McConnell  

LAB HEAD: Leslie M. Hicks

PROVIDER: PXD007221 | Pride | 2018-09-11

REPOSITORIES: Pride

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Publications

Investigating the effect of target of rapamycin kinase inhibition on the Chlamydomonas reinhardtii phosphoproteome: from known homologs to new targets.

Werth Emily G EG   McConnell Evan W EW   Couso Lianez Inmaculada I   Perrine Zoee Z   Crespo Jose L JL   Umen James G JG   Hicks Leslie M LM  

The New phytologist 20180724 1


Target of rapamycin (TOR) kinase is a conserved regulator of cell growth whose activity is modulated in response to nutrients, energy and stress. Key proteins involved in the pathway are conserved in the model photosynthetic microalga Chlamydomonas reinhardtii, but the substrates of TOR kinase and downstream signaling network have not been elucidated. Our study provides a new resource for investigating the phosphorylation networks governed by the TOR kinase pathway in Chlamydomonas. We used quan  ...[more]

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