Human hair shaft LC-MS/MS - Studies on the Proteome of Human Hair - Identification of Histones and Deamidated Keratins
Ontology highlight
ABSTRACT:
INSTRUMENT(S): Q Exactive
ORGANISM(S): Homo Sapiens (human)
TISSUE(S): Hair Shaft
SUBMITTER: 
Sunil Adav
LAB HEAD: Prof. Sze S K
PROVIDER: PXD007224 | Pride | 2018-01-30
REPOSITORIES: Pride
Publications
Studies on the Proteome of Human Hair - Identification of Histones and Deamidated Keratins.
Adav Sunil S SS Subbaiaih Roopa S RS Kerk Swat Kim SK Lee Amelia Yilin AY Lai Hui Ying HY Ng Kee Woei KW Sze Siu Kwan SK Schmidtchen Artur A
Scientific reports 20180125 1
Human hair is laminar-fibrous tissue and an evolutionarily old keratinization product of follicle trichocytes. Studies on the hair proteome can give new insights into hair function and lead to the development of novel biomarkers for hair in health and disease. Human hair proteins were extracted by detergent and detergent-free techniques. We adopted a shotgun proteomics approach, which demonstrated a large extractability and variety of hair proteins after detergent extraction. We found an enrichm ...[more]
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