FFPE oral cancer - Combining discovery and targeted proteomics reveals a prognostic signature in oral cancer

ABSTRACT: Laser Microdissection (LMD) associated to LC-MS/MS were used to analyze the proteome of neoplastic islands and stroma tumor of Formalin-Fixed and Paraffin Embedded (FFPE) OSCC tissues to identify proteins of prognostic value. Label-free protein quantification and statistical analysis revealed neoplastic islands proteins and from stroma tumor as correlated to clinicopathological data including lymphonode status and recurrence.

INSTRUMENT(S):

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Tongue

DISEASE(S): Oral Squamous Cell Carcinoma

SUBMITTER: Adriana Franco Paes Leme  

LAB HEAD: Adriana Franco Paes Leme Squina

PROVIDER: PXD007232 | Pride | 2018-09-10

REPOSITORIES: Pride