Proteomics,Multiomics

Dataset Information

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Human hepatic stellate cell-derived extracellular vesicles LC-MSMS


ABSTRACT: Activation and migration of hepatic stellate cells (HSCs) followed by matrix deposition are characteristics of liver fibrosis. Several studies have shown the importance of hepatocyte and endothelial cell-derived extracellular vesicles (EVs) in liver pathobiology. However, less is known about the role of HSC-derived EVs in liver diseases. In this study, we investigated the molecules released through HSC-derived EVs and whether these can promote fibrosis.

OTHER RELATED OMICS DATASETS IN: GSE140110

INSTRUMENT(S):

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Hepatic Stellate Cell, Liver

DISEASE(S): Hepatic Fibrosis

SUBMITTER: Enis Kostallari  

LAB HEAD: Vijay H. Shah, M.D.

PROVIDER: PXD007258 | Pride | 2018-10-18

REPOSITORIES: Pride