Ontology highlight
ABSTRACT:
INSTRUMENT(S): LTQ Orbitrap Velos
ORGANISM(S): Homo Sapiens (human)
TISSUE(S): Melanocyte, Cell Culture, Fibroblast
DISEASE(S): Melanoma
SUBMITTER: Andre Zelanis
LAB HEAD: André Zelanis
PROVIDER: PXD007265 | Pride | 2018-01-02
REPOSITORIES: Pride
Liberato Tarcísio T Pessotti Dayelle S DS Fukushima Isabella I Kitano Eduardo S ES Serrano Solange M T SMT Zelanis André A
Journal of proteomics 20171222
The imbalance of cellular homeostasis during oncogenesis together with the high heterogeneity of tumor-associated stromal cells have a marked effect on the repertoire of the proteins secreted by malignant cells (the secretome). Hence, the study of tumoral secretomes provides insights for understanding the cross-talk between cells within the tumor microenvironment as well as the key effectors for the establishment of the pre-metastatic niche in distant tumor sites. In this context, we performed a ...[more]